#5 seeds Newcastle also upset Derby, joining Solent and Hemel in the line up for next weekend's semi-finals.
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We take a look at the four quarter-finals below, with each heading clickable for live stats, plus links to live stats and live streams at the bottom of the page.
A 29-14 third quarter allowed top seeds Solent to knock off visitors Loughborough 78-61.
With the two sides tied 31-31 after the opening 20 minutes, a 17-3 streak to begin the second half broke the game open and pushed the Kestrels into a lead they'd never relinquish.
That run was a turning point for the hosts, with Orlan Jackman (19pts), Ian Smith (12pts) and Andre Arissol (12pts) all contributing as part of impressive overall performances.
Loughborough never managed to reduce their deficit to single digits once the difference passed the 10 point mark, spelling the end of the road for the #8 seeds.
Harrison Gamble enjoyed a 14 point, 12 rebound double as Joe Bielak also dropped 14 for the Riders.
Solent now progress to the semi-finals, hosting #5 seeds Newcastle next weekend.
Solent use a big third quarter to take out Loughborough in the quarter finals.— bbl fix (@BblFix) May 1, 2021
📸 Luke Simcock pic.twitter.com/NiJsGfyrX5
Worthing provided one of the upsets of the season as they grabbed a 94-89 road win against Thames Valley.
The #2 seeds were powerless to stop Thunder guard Tom Ward, who played the full 40 minutes to notch 35 points, 11 rebounds and four assists.
The regular season runners up would have been fearing the worst as Worthing came out firing to lead by as many as 14 in the second quarter, though coach Banks' side managed to regroup to trail by just a single point more than once down the stretch
The hosts never did find a way to pull level though, with their opponents always finding a key basket to keep their noses in front
Ward enjoyed support from Max Richardson (16pts, 12reb) and Howard Crawford (16pts), whilst Thames Valley were led by 24 points apiece from Blayne Freckleton and Taylor Johnson.
The 2017/18 playoff champs now move on to face Hemel as Thames Valley are left to wonder what might have been following an strong regular season campaign.
#3 seeds Hemel ended Bradford's playoff run as they secured a comfortable 81-69 victory on Saturday evening.
The Dragons were the only team to grab an upset in last weekend's opening round, but their post-season journey ends here as Mike Williams poured in 30 points for the hosts.
Both teams went into the half time break tied, but 37-37 quickly became 52-40 Hemel by the mid-point of the third quarter.
That left Bradford playing catch up and the Storm were in no mood to give up their spot in next weekend's semi-finals.
Player of the Year contender Greg Poleon provided a 15 point, 14 rebound double-double for Hemel, and Bode Adeluola scored 20 more.
David Walsh went 7-16 from deep for the visitors, eventually closing on 24 points.
In what was billed as one of the most closely-matched games of the weekend, Derby v Newcastle didn't disappoint as the #5 seeds sealed a narrow 84-82 win.
The spoils looked to belong to the Trailblazers who led by double digits in both the first and fourth period, but Newcastle won the final 6:02 23-11 to snatch a hard-fought victory.
Tied at 81 with 10 ticks remaining, both David Moya then Blake Bowman went one of two from the line to leave the scores tied once again, with Brandon Federici getting the deciding trip to the charity stripe with four seconds on the clock.
The Newcastle guard sank both shots, and as Derby's last gasp effort hit the shot clock and the buzzer sounded, Newcastle were left to celebrate a place in the last four.
Federici finished on a team-high 24 points, with Ronald Blain just a rebound away from a double-double on 21 points and nine boards.
Jacob Conway top scored for the Trailblazers, he had 26.
3:30pm - #1 Team Solent Kestrels 78-61 #8 Loughborough Riders - LIVE STATS/LIVE STREAM
5pm - #3 Hemel Storm 81-69 #11 Bradford Dragons - LIVE STATS/LIVE STREAM LOCATION
6:30pm - #2 Thames Valley Cavaliers 89-94 #7 Worthing Thunder - LIVE STREAM/LIVE STREAM
Main image credit - Luke Simcock