Coach Drane's side are now four points clear of nearest challengers Loughborough, whilst the Cavs second win in a row pulls their record back to .500.
There's a recap of both games below, and each result is also clickable if you wish to view the live stats.
A huge 24-point, 19-rebound double-double from Katherine Goldsby helped TVC grab their second win of the season, beating Nottingham 72-61.
Goldsby was a problem for the visitors throughout, going 9-18 from the floor whilst helping her side dominate the rebound battle 67-34.
The hosts won the opening frame 18-11 before splitting the second 18-18 to hold a 36-29 advantage at the half.
The visitors would come into the contest in the third, enjoying their first lead of the afternoon with 3:05 remaining before ending the quarter up 47-46.
The fourth would belong to Thames Valley though, winning it 26-14 as Goldsby clocked up 12 points and seven boards in that frame alone.
The talented guard was supported by Emma Delea, who finished with 16 points, and Ezekiela Lisk, who was just short of a double-double with eight points and 15 rebounds.
Mady Burdett top scored for NTU with 13 points to go with 10 boards.
Tog dogs Ipswich ran out comfortable winners against bottom side BA London Lions, winning 90-56 on Saturday afternoon.
Ahead by more than 20 midway through the second, the visitors did battle back before the half to reduce the deficit to 10.
The hosts would win both quarters after the break though, including a 28-10 fourth to cap a dominant performance against the winless Lions.
Harriet Welham was in dazzling form, finishing with a 29 point, 10 rebound, 10 assist triple-double, as Esther Little controlled the glass with 22 rebounds. Dani Cazey also impressed for Ipswich, scoring 27 points.
Without the services of talented forward Leia Edwards, Barking were paced by Deborah Somoye, who was a single point away from a double-double with nine points and 10 rebounds. Ann Sheaia led the team in scoring with 12.
Main image credit - Luke Simcock